50.有關抗癌化學治療之目的,下列敘述何者正確?
(A) neoadjuvant therapy之目的在根除性的手術後清除微轉移(micrometastases)
(B) adjuvant therapy之目的在降低腫瘤大小,以利手術進行
(C) induction therapy之目的在堅固前一階段化學治療所達到的成果
(D) palliative therapy之目的在阻擋癌細胞進一步的蔓延
統計: A(205), B(591), C(775), D(2606), E(0) #882547
詳解 (共 10 筆)
adjuvant : main therapy之後的化療,減少轉移機率
salvage : 一線失敗之後用的救援(第二線) (仍以治癒為目標)
palliative : 通常for已轉移的病人,減少癌症的不適和癌細胞的生長
Adjuvant chemotherapy - Chemotherapy given to destroy left-over (microscopic) cells that may be presentafter the known tumor is removed by surgery. Adjuvant chemotherapy is given to prevent a possible cancer reccurrence.
Neoadjuvant chemotherapy - Chemotherapy givenprior to the surgical procedure. Neoadjuvant chemotherapy may be given to attempt to shrink the cancer so that the surgical procedure may not need to be as extensive.
Induction chemotherapy - Chemotherapy given to induce a remission. This term is commonly used in the treatment of acute leukemias.
Consolidation chemotherapy - Chemotherapy given once a remission is achieved. The goal of this therapy is to sustaina remission. Consolidation chemotherapy may also be called intensification therapy. This term is commonly used in the treatment of acute leukemias.
Maintenance chemotherapy - Chemotherapy given in lower doses to assist in prolonging a remission. Maintenance chemotherapy is used only for certain types of cancer, most commonly acute lymphocytic leukemias and acute promyelocytic leukemias.
First line chemotherapy - Chemotherapy that has, through research studies and clinical trials, been determined to have the best probability of treating a given cancer. This may also be called standard therapy.
Second line chemotherapy - Chemotherapy that is given if a disease has not responded or reoccurred after first line chemotherapy. Second line chemotherapy has, through research studies and clinical trials, been determined to be effective in treating a given cancer that has not responded or reoccurred after standard chemotherapy. In some cases, this may also be referred to as salvage therapy.
Palliative chemotherapy - Palliative is a type of chemotherapy that is given specifically to address symptom management without expecting to significantly reduce the cancer.
(A) induction chemotherapy的目標為快速達到complete remission,恢復造血功能
(B) 只要能達到完全緩解,不論多少次的induction chemotherapy都有好的預後
(C) 最重要的預後因子為癌症期別
(D) antimicrotubule藥品為化學治療的主幹
化療為第一線療法為induction therapy,之後的consolidation為了進一步根除剩下的癌細胞