6. P/O ratio in electron transport and oxidative phosphorylation is defined as: (A) Molecules of phosphate released from ATP per oxygen utilized by muscle tissue. (B) Molecules of ATP formed per two electrons flowing through the electron transport chain. (C) Pi uptake per oxygen atom by mitochondria. (D) Ratio of atoms of phosphorus to oxygen in phosphate (Pi). (E) None of the above.

1. Compare the two reaction coordinate diagrams below and select the answer that correctly describes their relationship. In eachcase, the single intermediate is the ES complex.Free energy, (A) Diagram (a) describes a strict "lock and key" model, whereas diagram (b) describes a transition-state complementarity model. (B) The activation energy for the catalyzed reaction is #5 in diagram (a) and is #7 in diagram (b). (C) The activation energy for the uncatalyzed reaction is given by #5 + #6 in diagram (a) and by #7 + #4 in diagram (b). (D) The contribution of binding energy is given by #5 in diagram (a) and by #7 in diagram (b). (E) The ES complex is given by #2 in diagram (a) and #3 in diagram (b).

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