試題詳解

7. From the study of a crystal structure, a trigger loop is revealed in eukaryotic RNA polymerase II. What is the possible function of the trigger loop?
(A) The trigger loop may initiate the dissociation of the RNA-DNA hybrid during transcription.
(B) The trigger loop presumably stabilizes the substrate association with the active site of RNA polymerase II, and is involved in nucleotide selection against improper nucleotides.
(C) The trigger loop is involved in maintaining dissociation of the RNA-DNA hybrid during transcription.
(D) The trigger loop is used to maintain dissociation of template DNA (i.e. transcription bubble) during transcription.
(E) The trigger loop is important for removing the misincorporated nucleotide during transcription.