73. Which of the following is NOT related to RNA-RNA interaction?
(A) guide RNA
(B) Wobble
(C) Shine-Dalgarno sequence
(D) snRNA
(E) None of the above

69. Which of the following enzymatic cofactors and enzymes is NOT matched? (A) Biotin for pyruvate carboxylase (B) NAD+ for glucose 6-phosphate dehydrogenase (C) Pyridoxal phosphate (PLP) for aminotransferases (D) Thiamine pyrophosphate (TPP) for pyruvate decarboxylase (E) Vitamin B12 for methylmalonyl-CoA mutase

70. How many ATP can be net produced in a 14-carbon fatty acid degradation to CO2 and H2O? (A) 88 (B) 92 (C) 94 (D) 96 (E) 98

71. Fatty acids are carboxylic acids with hydrocarbon chains ranging from ________ carbons long. (A) 12 to 24 (B) 4 to 36 (C) 6 to 24 (D) 6 to 36 (E) 12 to 32

72. The molecular weight of Protein A (pI = 4.0), B (pI = 6.8), and C (pI = 8.5) is 14 kDa, 24 kDa, and 30 kDa, respectively. All of them are monomer proteins. Which of the following statements is CORRECT? (A) Protein A elutes out first, when you use gel filtration column to separate the mixture of those three proteins. (B) Protein C is the one that moves fastest, when you separate the mixture of those three proteins by SDS-PAGE. (C) As shown in the right figure, you can use this isoelectric focusing apparatus to separate those three proteins. (D) When you use a DEAE ion exchange column and 10 mM Tris-Cl, pH 7.0 buffer to separate these three proteins, Protein A will be bound by this column. (E) None of the above

74. (1) Arg； (2) Asp； (3) Gly； (4) Cys； (5) His； (6) Ser； (7) Thr. Which of the followings does NOT appear in the preceding seven amino acid residues? (A) The amino acid residue in zinc finger to coordinate zinc atom (B) The amino acid residue in O-link glycoprotein to link protein and oligosaccharide (C) The amino acid residue in Type I topoisomerase to act as a nucleophile to cut DNA (D) The amino acid residue in terminal proteins of adenovirus to link nucleotides and protein (E) None of the above

75. Which of the following compounds is the substrate of ribonucleotide reductase? (A) AMP (B) TDP (C) GTP (D) CDP (E) dAMP

76. (1) Ribozyme； (2) Okazaki fragment； (3) DNA polymerase needs an RNA primer but RNA polymerase doesn’t； (4) de novo biosynthesis of purine and pyrimidine； (5) retrovirus； (6) thermostable DNA polymerase. How many of the preceding items support the hypothesis that RNA appears before DNA? (A) 2 (B) 3 (C) 4 (D) 5 (E) 6

77. (1) release of acetyl-CoA； (2) release of CO2； (3) release of NADH. Pyruvate dehydrogenase can convert pyruvate into acetyl-CoA, NADH, and CO2. What is its reaction order of preceding three steps? (A) (1) → (2) → (3) (B) (1) → (3) → (2) (C) (2) → (1) → (3) (D) (2) → (3) → (1) (E) (3) → (1) → (2)

78. Xeroderma pigmentosum is caused by a defect in which DNA repair pathway. (A) Repair of oxidative damage (B) Daughter-strand gap repair (C) Base excision repair (D) Mismatch repair (E) Nucleotide excision repair

79. The reverse transcriptases possess the function of ① RNA-directed DNA polymerase activity ② Primase ③ DNA-directed DNA polymerase activity ④ RNase H activity ⑤ Helicase (A) ①②③ (B) ①②④ (C) ①②⑤ (D) ①③④ (E) ①③⑤