74.Telithromycin產生膽鹼拮抗作用,與結構中下列何種基團有關?
(A)piperidine
(B)pyridine
(C)pyrrolidine
(D)pyrimidine

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統計: A(715), B(1632), C(1830), D(856), E(0) #2756098

詳解 (共 6 筆)

#5333559
Telithromycin  (Te...
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結構補充 Telithromycin ...
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#5014593
Significant controve...
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For 蛋白合成抗生素 —------...
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Telithromycin, a semi-synthetic erythromycin derivative, belongs to a new chemical class of antibiotics called ketolides. Ketolides have been recently added to the macrolide-lincosamide-streptogramin class of antibiotics. Similar to the macrolide antibiotics, telithromycin prevents bacterial growth by interfering with bacterial protein synthesis. Telithromycin binds to the 50S subunit of the 70S bacterial ribosome and blocks further peptide elongation. Binding occurs simultaneously at to two domains of 23S RNA of the 50S ribosomal subunit, domain II and V, where older macrolides bind only to one. It is used to treat mild to moderate respiratory infections.
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私人筆記 (共 2 筆)

私人筆記#3877469
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Macrolides 巨環類 機轉:【...
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私人筆記#6842766
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