試題詳解

78. Defect in metabolism of phenylalanine causes phenylketounia and alkaptonuria. Which of the following statements are correct? ① A person with phenylketonuria will convert phenylalanine to phenylpyruvate. ② A person suffering from phenylketonuria on consumption food containing high phenylalanine may lead to the accumulation of tyrosine. ③ A person with phenylketonuria is advised not to consume aspartame.④ Alkaptonuria is due to defect in phenylalanine hydroxylase. ⑤ A person suffering from phenylketonuria on consumption food containing high phenylalanine may lead to the accumulation of acetoacetyl-CoA.
(A)①②
(B)①③
(C)①④
(D)②③
(E)②⑤