試題詳解

10. Which statement is not true for class I and III promoters in the eukaryotes?
(A) For eukaryotic RNA polymerase III-dependent promoters (class III promoter), the TATA box is recognized by the general transcription factor TFIIIB.
(B) For class I promoter in human, the core-binding factor SL1 is required to recruit RNA polymerase I.
(C) TFIIIB acts as an assembly factor that binds to the internal promoter and helps TFIIIA to bind to a region just upstream of the transcription start site.
(D) TFIIIA is required for transcription of the 5S rRNA genes, but not for the tRNA genes.

(E) Although class I promoters are variable in sequence across species, they do contain the AT-rich initiator with a conserved sequence.