試題詳解

11. Please choose one wrong statement for the roles of different general transcription factors in eukaryotic RNA polymerases.
(A) TATA-binding factor (TBP) is also required for transcription in the Archaea.
(B) The TBP-associated factor 1 (TAF1) serves as an assembly factor around which other TAFs can aggregate and also contains a histone acetyltransferase activity.
(C) TFIIB is a general transcription factor with its C-terminal domain to interact with RNA polymerase II and can determine the direction of transcription.
(D) TBP-free TAF-containing complex (TFTC) can sponsor the formation of preinitiation complex of RNA polymerase II without the presence of TFIID.

(E) The negative cofactor 2 (NC2) can stimulate RNA polymerase II-related gene transcription from downstream promoter element (DPE)-containing promoters.