28.下列何者為妊娠噁心、嘔吐的首選用藥？
(A)ascorbic acid
(B)folic acid
(C)pyridoxine
(D)thiamine

Pyridoxine (vit B6)

妊娠引起之噁心、嘔吐、皮膚炎、維他命B6缺乏症。 

60.下列何者是孕婦噁心、嘔吐的後線用藥？ 
(A)doxylamine 12.5 mg po tid + pyridoxine 10～25 mg po tid 
(B)pyridoxine 10～25 mg po tid 
(C)diphenhydramine 25～50 mg po q8h 
(D)methylprednisolone 16 mg po q8h x 3 days, then taper over 2 weeks 

ANTIEMETIC USE DURING PREGNANCY

•Initial management of nausea and vomiting of pregnancy (NVP) often involves dietary changes and/or lifestyle modifications.

•Pyridoxine (10–25 mg one to four times daily) is recommended as first-line therapy with or without doxylamine (12.5–20 mg one to four times daily). Patients with persistent NVP or who show signs of dehydration should receive IV fluid replacement with thiamine. Ondansetron 2 to 8 mg orally/IV every 8 hours as needed may alleviate NVP.

一般婦女葉酸 0.4mg/d

AED治療要4mg/d

vitamin B12  cyanocobalamin 可以用於治療惡性貧血，巨母細胞貧血。(補充7F)

ref:台灣醫界 2012, Vol.55, No.7