32. Telomerase is an enzyme can solve the problem of replication at the ends of linear chromosomes. How does it work? (A) Repetitive sections of DNA can range from a single nucleotide to hundreds of nucleotides. Three nucleotides of smaller is a microsatellite. (B) It adds 5' cap and 3’ polyA on chromosome that resists degradation by nucleases. (C) It works like regular DNA polymerase (3'-5') except does not need DNA template strand to direct synthesis. Uses intrinsic RNA strand to synthesize GGGTTA sequence. (D) It causes specific double-strand DNA breaks and rejoins the blunt ends on both strands. (E) It adds numerous methylated GC pairs which resist hydrolysis and maintain chromosome integrity.