試題詳解

34. Which of the following consideration for the use of adjuvants in the older persons is correct?
(A) amitriptyline has more anticholinergic adverse effects than second-generation tricyclic antidepressants (nortriptyline or desipramine)
(B) Serotonin and norepinephrine reuptake inhibitors (SNRIs) have fewer of these undesired effects from tricyclic antidepressants but a greater risk of drug interactions and elevation of liver enzymes
(C) Antiepileptic drugs are first-line agents to treat neuropathic pain in older persons with labeled indications
(D) carbamazepine may be useful for neuropathic pain, but less ideal in older adults due to drug interactions, renal, liver, and hematologic toxicity
(E) all of the above are correct descriptions for adjuvants use in older persons