63.陳先生59歲,有冠狀動脈心臟疾病,最近LDL 200 mg/dL、HDL 42 mg/dL、TG 180 mg/dL。下列何者為首選
用藥?
(A)gemfibrozil
(B)atorvastatin
(C)cholestyramine
(D)niacin
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統計: A(150), B(2700), C(36), D(160), E(0) #2972417
統計: A(150), B(2700), C(36), D(160), E(0) #2972417
詳解 (共 10 筆)
#5589080
因為有冠狀動脈心臟疾病則LDL建議小於100mg/dL。
選擇降低LDL效果佳的高強度statin類(atorvastatin, rosuvastatin)。
選擇降低LDL效果佳的高強度statin類(atorvastatin, rosuvastatin)。
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#5714468
標準TC<200 ; TG<150 ; LDL<100
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#6095162
55.下列何種狀況,不適合使用Friedewald公式[LDL-C = TC– (HDL-C + TG/5)]計算低密度脂蛋白膽固醇(LDL- C)?[註:TC, total cholesterol; TG, triglycerides]
(A) TC介於200~400 mg/dL之間
(B) TG高於400 mg/dL
(C) 病人禁食達10小時
(D) HDL-C=50 mg/dL
專技 - 藥物治療學 -108年 - 108-2 專技高考_藥師(二):藥物治療學#78193
答案:B
46.有關Friedewald法計算LDL-cholesterol(LDL-C),下列算式何者正確?
(A) [LDL-cholesterol] = [Total cholesterol] - [HDL-cholesterol] - [Triglyceride]/5
(B) [LDL-cholesterol] = [Total cholesterol] - [VLDL-cholesterol] - [Triglyceride]/5
(C) [LDL-cholesterol] = [Total cholesterol] - [HDL-cholesterol] - [VLDL]/5
(D) [LDL-cholesterol] = [Total cholesterol] - [VLDL-cholesterol] - [HDL]/5
生物化學與臨床生化學 -108年 - 108-2 專技高考_醫事檢驗師:生物化學與臨床生化學#78209
答案:A
(A) [LDL-cholesterol] = [Total cholesterol] - [HDL-cholesterol] - [Triglyceride]/5
(B) [LDL-cholesterol] = [Total cholesterol] - [VLDL-cholesterol] - [Triglyceride]/5
(C) [LDL-cholesterol] = [Total cholesterol] - [HDL-cholesterol] - [VLDL]/5
(D) [LDL-cholesterol] = [Total cholesterol] - [VLDL-cholesterol] - [HDL]/5
生物化學與臨床生化學 -108年 - 108-2 專技高考_醫事檢驗師:生物化學與臨床生化學#78209
答案:A
1. 此公式適合測空腹,禁食達10小時是完美的空腹~
The Friedewald formula is applied to lipid values measured in the fasted state. In a non-fasting patient, the contribution of post-prandial chylomicrons to the total lipoprotein pool makes the formula much less accurate.
2. The formula is valid only if the total triglyceride concentration is less than 400 mg/dL (4.516 mmol/L).
In patients with more pronounced hypertriglyceridemia, LDL cholesterol levels must be measured directly (direct LDL) by ultracentrifugal single spin analysis or immunoprecipitation technique [8].
The Friedewald formula is applied to lipid values measured in the fasted state. In a non-fasting patient, the contribution of post-prandial chylomicrons to the total lipoprotein pool makes the formula much less accurate.
2. The formula is valid only if the total triglyceride concentration is less than 400 mg/dL (4.516 mmol/L).
In patients with more pronounced hypertriglyceridemia, LDL cholesterol levels must be measured directly (direct LDL) by ultracentrifugal single spin analysis or immunoprecipitation technique [8].
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#5772193
有冠狀動脈心臟疾病,最近LDL 200 mg/dL、HDL 42 mg/dL、TG 180 mg/dL
LDL 200 大於正常值100
TG也偏高
通常會先使用STATIN藥物把LDL降下來
LDL 200 大於正常值100
TG也偏高
通常會先使用STATIN藥物把LDL降下來
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