64. Which of the following statements about RNA interference (RNAi) is FALSE?
(A) MicroRNAs (miRNAs) or short-interfering RNAs (siRNAs) interfere with the proper expression of mRNAs.
(B) Single-stranded pre-siRNA is cut by dicer and release typically 22bp RNA.
(C) Single-stranded siRNA associates with RISC protein and bind to target mRNA.
(D) High complementarity of siRNA and target mRNA result in mRNA degradation or translation inhibition.
(E) Low complementarity of siRNA and target mRNA result in mRNA degradation or translation inhibition.
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統計: A(1), B(27), C(6), D(2), E(32) #937773
統計: A(1), B(27), C(6), D(2), E(32) #937773
詳解 (共 6 筆)
#5258767
有人可以解答D和E嗎?不管complementarity高低都一樣?
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#5414293
我也想知道
E不是需完全互補才有辦法作用嗎?
siRNA is also similar to miRNA, however, miRNAs are derived from shorter stemloop RNA products, typically silence genes by repression of translation, and have broader specificity of action, while siRNAs typically work by cleaving the mRNA before translation, and have 100% complementarity, thus very tight target specificity
節錄自維基
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