64. Which of the following statements about RNA interference (RNAi) is FALSE?
(A) MicroRNAs (miRNAs) or short-interfering RNAs (siRNAs) interfere with the proper expression of mRNAs.
(B) Single-stranded pre-siRNA is cut by dicer and release typically 22bp RNA.
(C) Single-stranded siRNA associates with RISC protein and bind to target mRNA.
(D) High complementarity of siRNA and target mRNA result in mRNA degradation or translation inhibition.
(E) Low complementarity of siRNA and target mRNA result in mRNA degradation or translation inhibition.

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統計: A(1), B(27), C(6), D(2), E(32) #937773

詳解 (共 6 筆)

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(B) Double-stranded ...
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(D) High complementa...
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有人可以解答D和E嗎?不管complementarity高低都一樣?

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我也想知道
E不是需完全互補才有辦法作用嗎?
siRNA is also similar to miRNA, however, miRNAs are derived from shorter stemloop RNA products, typically silence genes by repression of translation, and have broader specificity of action, while siRNAs typically work by cleaving the mRNA before translation, and have 100% complementarity, thus very tight target specificity 

節錄自維基 

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104年 - 104 學士後西醫:普通生...

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