73. Diabetes insipidus is a disorder marked by production of abnormally large in volume and very dilute urine. It can cause
severe dehydration. The mechanism(s) attributing the disorder can be
(A) mutations that prevent ADH production
(B) mutations that inactivate aquaporin
(C) mutations that inactivate insulin receptor
(D) both A and B
(E) all of the A, B, and C
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統計: A(2), B(3), C(2), D(26), E(11) #1122175
統計: A(2), B(3), C(2), D(26), E(11) #1122175
詳解 (共 1 筆)
#6496782
(A) ✔ 正確。這會造成中樞型尿崩症(Central diabetes insipidus),因為下視丘或腦垂體無法製造或釋放ADH。
(B) ✔ 正確。這會導致腎性尿崩症(Nephrogenic diabetes insipidus),即使有ADH,腎臟因為aquaporin-2功能異常無法回收水分。
(C) ✘ 錯誤。這跟糖尿病(Diabetes mellitus)相關,不會導致尿崩症,跟尿液稀釋無直接關聯。
(D) ✔ 正確。
(E) ✘ 錯誤。
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