74.下列何種抗癌藥物會造成interstrand cross-linking of DNA?
(A)Busulfan
(B)Procarbazine
(C)5-FU
(D)Cyclophosphamide
(E) A、D
答案:登入後查看
統計: A(134), B(47), C(124), D(237), E(5761) #624479
統計: A(134), B(47), C(124), D(237), E(5761) #624479
詳解 (共 9 筆)
#1408238
interested:Busulfan. Cyclophosphamide. Carmustine
intrastrand: Cisplatin.
皆有:Melphalan
不產生cross-linking: Dacarbazine
298
4
#1432362
是的
inhibits DNA & RNA synthesis via formation of carbonium ions; cross links DNA strands (interstrand and intrastrand crosslinking) causing miscoding breakage and subsequently DNA replication failure
28
2
#1428962
Melphalan是inter 和 intra 都有嗎?
28
0
#3750344
Procarbazine 是形成自由基 和O6有關
Busulfan 和肺纖維化有關
Cyclophosphamide 的Acrolein產物和出血性膀胱炎有關
21
1
#1395278
AD皆為烷化劑
15
1
#910037
9
3
#910031
原本答案為A,修改為E
8
3