1. Indicate the order in which the following steps occur in the production of a mature mRNA.1. initiation of transcription2. splicing3. addition of 5′ cap4. addition of poly（Ａ） tail5. transport to cytoplasm
(A) 1, 2, 3, 4, 5
(B)1，3，4，2，5
(C) 1, 3, 4, 5，2
(D) 1, 3, 4, 2, 5 (Ε) 1, 3, 2, 4, 5

22. 若 sinθ cos= ，則 tanθ +cot θ之值為何？ (A) (B) 1 (C) (D)

23. 已知點 P(a-b,ab) 在坐標平面的第四象限，則下列敘述何者正確？ (A) A(a,-b )  在第一象限 (B) 在第二象限 (C)在第三象限 (D)在第四象限

24. 若< θ<π 且 sinθ= ，則tan2θ 之值為何？ (A) (B) (C) (D)

25. 若f(x)=x4+5x3+x-1，g(x)=x2-2 且 f (x) 除以 g(x) 的餘式為ax+b ( a , b為常數)，則2a-3b 為何？ (A) -27 (B) -7 (C) 5 (D) 13

複選題2. Which one of the following statements about mRNA stability is true? (A) Degradation always proceeds in the 5' to 3' direction. (B) 5' poly（Ａ） tail protects RNA from degradation. (C) Secondary structure in mRNA (hairpins, for example) slows the rate of degradation. (D) In general, bacterial mRNAs have longer half-lives than do eukaryotic mRNAs. (E) Rates of mRNA degradation are always at least 10-fold slower than rates of mRNA synthesis.

3. Phospholipids with short or unsaturated fatty acyl chains can: (A) decrease membrane fluidity. (B) increase membrane fluidity. (C) cause biomembranes to become thicker. (D) allow hydrophilic molecules to flip in the lipid bilayer. (E) allow hydrophilic molecules to diffuse across the lipid bilayer.

4. Select the correct statement listed below. 　1. The nuclear pore complex allows for passive diffusion of smaller molecules. 　2. The nuclear pore complex allows for import of proteins. 　3. The nuclear pore complex allows for active transport of very large molecules. (A) Only 3 is correct. (B) 1, 2 are correct. (C) 1, 3 are correct. (D) 2, 3 are correct. (E) All of the above are correct.

5. Glycosylphosphatidylinositol modification serves to target proteins to: (A) RER. (B) Golgi. (C) Plasma membrane. (D) Nucleus. (E) Lysosome

複選題6. Glycosylation, a post-translational modification to proteins, occurs in the: (A) RER. (B) Golgi. (C) Proteasome. (D) Endosome. (E) Mitochondria.

7. Which one is NOT found in mitotic spindles? (A) a-tubulin (B) ẞ-tubulin (C) y-tubulin (D) Microtubule associated proteins (E) Motor proteins