試題詳解

10. A patient is diagnosed with a rare mutation that impairs the ability of intracellular receptors to dimerize upon hormone binding. Which of the following hormonal responses would be most severely affected?
(A) insulin-mediated glucose uptake in muscle cells
(B) epinephrine-induced glycogen breakdown in hepatocytes
(C) cortisol-induced transcriptional activation in target tissues
(D) parathyroid hormone (PTH)-induced calcium mobilization
(E) growth hormone (GH)-induced IGF-1 secretion from the liver