17.有關azelastine之敘述,下列何者正確?
(A)以loratadine治療不佳的病人,使用azelastine同樣無效
(B)有口服劑型
(C)鼻噴劑不會全身性吸收
(D)鼻噴劑有嗜睡副作用
答案:登入後查看
統計: A(203), B(914), C(1690), D(2629), E(0) #2038974
統計: A(203), B(914), C(1690), D(2629), E(0) #2038974
詳解 (共 10 筆)
#4834527
azelastine是二代抗組織胺
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#3754146
(A) azekastine對loratadine治療不佳病人有效
CONCLUSIONS: Azelastine nasal spray is an effective treatment for patients with seasonal allergic rhinitis who do not respond to loratadine and is an alternative to switching to another oral antihistamine or to using multiple antihistamines. https://www.ncbi.nlm.nih.gov/m/pubmed/12952117/
(B) 目前台灣核可的azelastine藥品許可證只有鼻噴劑型 國外有眼用劑型(uptodate 有收錄

(C)(D)有全身性副作用 會頭痛頭暈疲倦嗜睡等.......
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#3504644

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#6155769
CD應該可以想成:會全身性吸收,所以才會造成嗜睡副作用!
不然如果只作用在鼻子裡的受器就不會影響到中樞了
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