試題詳解

57. Metformin is a drug for the treatment of type 2 diabetes. The drug has a wide action. Which of the following mechanisms is most likely to be true?
(A) Tt improves the sensitivity of cells to insulin, primarily by stimulating glucose uptake by glucose transporters in peripheral tissues.
(B) It inhibits the activity of AMP-activated protein kinase.
(C) It activates AMP deaminase and decreascs cellular AMP levels.
(D) It inhibits insulin binding to receptors and reduces the receptor's tyrosine kinase activity.
(E) It enhances gluconeogenesis in the liver.