63. What enzyme(s) is required for the cleavage of the unmethylated strand during the mismatched repair?
(A) MutL
(B) MutH
(C) MutS
(D) DNA helicase II/exonuclease VII
(E) Exonuclease I/exonuclease X

59. In additional to the potential of many cancer cells to grow uncontrollably, which of the following scenarios is most likely to result in a tumor? (A) Lack of appropriate cell death (B) The order of cell cycle stages can be changed (C) Inability to form spindles (D) Failure of cells to enter the S shape (E) Most cancer cells are senescent

60. In human bodies, which functional area is mainly located in the occipital lobe of the brain? (A) Hearing (B) Reading (C) Smell (D) Speech (E) Vision

61. What amino acid is often phosphorylated by active insulin receptor? (A) Serine (B) Threonine (C) Tyrosine (D) Histidine (E) Arginine

複選題62. What compound offers the one-carbon unit to produce N5 , N10 -methylene tetrahydrofolate in one carbon metabolism? (A) Methionine (B) Serine (C) S-Adenosyl methionine (D) Choline (E) Glycine

64. What domain(s) of regulatory proteins for gene regulation is involved in dimerization? (A) Helix-turn-helix (B) Helix-loop-helix (C) Zinc finger (D) Homeodomain (E) All of the above

65. Which statement for hemoglobin (the oxygen-binding protein in red blood cells) is FALSE? (A) Hemoglobin exists in T and R states and R state prefers to bind oxygen. (B) Oxygen binding converts hemoglobin from T to R state. (C) Oxygen binding to hemoglobin is both allosteric and cooperative. (D) Hemoglobin also binds H+ and CO2 to lessen the affinity for O2. (E) Oxygen binding is also regulated by 2,3-bisphosphoglycerate, which stabilizes R state.

66. For treatment of AIDS, which is NOT a target for the approved drugs? (A) CD4 (B) reverse transcriptase (C) neuraminidase (D) protease (E) integrase

67. Which of the following receptors and their types does NOT match? (A) Insulin receptor is a G-protein-coupled receptor. (B) Epidermal growth factor receptor is a receptor tyrosine kinase. (C) Acetylcholine receptor is a gated ion channel. (D) Integrin receptor is an adhesion receptor. (E) Steroid receptor is a nuclear receptor.

68. Which of the following compounds has the highest (the most negative) standard free energy of hydrolysis? (A) ATP (to ADP) (B) ADP (to AMP) (C) AMP (to adenosine) (D) Glucose 6-phosphate (to glucose) (E) Acetyl-CoA (to acetate)

69. Which of the following enzymatic cofactors and enzymes is NOT matched? (A) Biotin for pyruvate carboxylase (B) NAD+ for glucose 6-phosphate dehydrogenase (C) Pyridoxal phosphate (PLP) for aminotransferases (D) Thiamine pyrophosphate (TPP) for pyruvate decarboxylase (E) Vitamin B12 for methylmalonyl-CoA mutase