74. Enzyme kinetics provide the values of the Michaelis constant KM and the turnover number Kcat. Which of the following statements is true?
(A) KM indicates the substrate concentration at which the reaction rate is Vmax
(B) KM measures the rate of the catalytic process
(C) KM indicates the substrate binding affinity; the smaller KM indicates the higher substrate binding affinity
(D) In enzyme inhibition study, a competitive inhibitor decreases the apparent KM
(E) All of the above
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