試題詳解

90. Which of the following statements is correct regarding reversible inhibition of enzymes?

① The catalytic efficiency of enzyme is  in the presence of competitive inhibitors.

② Competitive inhibitors are substrate analogs or transtion state analogs.

③ Uncompetitive inhibitors combine only with enzyme-substrate complex.

④ In the presence of inhibitors, the initial rate of enzyme-catalyzed reactions is positively correlated with substrate concentration.

⑤ The binding of noncompetitive inhibitors to enzymes is inhibited by substrate.
(A) ①②③
(B) ②③④
(C) ③④⑤
(D) ①③④
(E) ②④⑤