2. What product would be obtained for the following reaction?
(A) CH₃(CH₂)₃C≡CCH₂OH
(B) CH₃(CH₂)₃C≡CCHO
(C) CH₃(CH₂)₃C≡CH
(D) CH₃(CH₂)₃C≡CNMe₂
(E) None of the above.

89. Which step about regulation of gene expression by insulin is not correct? (A) Insulin receptor binds insulin and undergoes autophosphorylation. (B) Insulin receptor binds IRS-1 on its Tyr residues. SH3 domain of Grb2 binds to phosphorylated Tyr of IRS-1. (C) Sos binds to Grb2, then to Ras, causing GDP release and GTP binding to Ras. (D) Activated Ras binds and activates Raf-1. (E) Raf-1 phosphorylates MEK. MEK phosphorylates MAPK, activating it.

90Which description about β-adrenergic pathway (a G-protein coupling receptor; GPCR) is not correct? (A) The receptor is a 7-transmembrane protein. (B) Epinephrine binds to a GPCR. (C) The occupied receptor could cause the replacement of the GDP bound to GS (stimulatory G protein) by GTP, activating GS. (D) GSβ moves to adenylyl cyclase and activates it to synthesize cAMP. (E) cAMP activates PKA to trigger cellular response.

1. Rank the following monomers in order of increasing reactivity toward cationic polymerization (least reactive to most reactive). (A) III, IV, I, II (B) II, I, IV, III (C) I, II, IV, III (D) IV, III, I, II (E) I, II, III, IV

3. Which two have the same molecular geometry? (A) I, II (B) III, IV (C) I, V (D) II, V (E) IV, V

4. Which nitrogen(s) have more basic? (A) I (B) II (C) III (D) I, II, and III are acidic (E) None of the above.

5. Rank the acidity of the following compounds. (A) I ＞ IV ＞ III ＞ II (B) I ＞ III ＞ IV ＞ II (C) IV ＞ II ＞ I ＞ III (D) II ＞ I ＞ IV ＞ III (E) None of the above.

6. What is the order of increasing acidity for the following compounds? (A) IV ＜ I ＜ II ＜ III (B) III ＜ II ＜ I ＜ IV (C) III ＜ II ＜ IV ＜ I (D) IV ＜ II ＜ I ＜ III (E) I ＜ IV ＜ II ＜ III

7. Which of these substances contains both covalent and ionic bonds? (A) HN3 (B) NH4Cl (C) H2O2 (D) XeF2 (E) PCl5

8. Choose the correct product of the following reaction? (A) (B) (C) (D) (E)

9. How many monochloro substituted products C6H13Cl you might obtain by reaction of 2-methylpentane with Cl2? (A) 1 (B) 2 (C) 3 (D) 4 (E) 5