25 下列關於 5-fluorouracil(5-FU)用於癌症治療作用機轉的敘述,何者正確?
(A)為 folate 的類似物,可干擾 tetrahydrofolate 的形成
(B)為 inosine monophosphate(IMP)的類似物,可抑制 IMP-dehydrogenase 的活性
(C)其活化物可與 thymidylate synthase 結合並抑制其活性
(D)可抑制 fatty acid synthase 的活性
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統計: A(3), B(2), C(19), D(0), E(0) #1373479
統計: A(3), B(2), C(19), D(0), E(0) #1373479
詳解 (共 2 筆)
#3107302
(Wikipedia) Fluorouracil is in the antimetabolite and pyrimidine analog families of medications.[5][6] How it works is not entirely clear but believed to involve blocking the action of thymidylate synthase and thus stopping the production of DNA.[2]
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