3.關於第一型單純疱疹感染所引起的病症之敘述,下列何者正確?
(A)大部分的原發性疱疹齦口炎(primary herpetic gingivostomatitis)發生在 70 歲以上的患者
(B)再發性疱疹感染(recurrent herpetic infection)只出現在下唇黏膜
(C)如果感染發生在拇指或食指,稱為疱疹指頭炎(herpetic whitlow)
(D)組織病理學上可以看見游離的漂浮細胞-詹克細胞(free floating cell-Tzanck cell)是其診斷特徵
統計: A(19), B(22), C(1609), D(122), E(0) #3062458
詳解 (共 5 筆)

如果發生在老年人,多半會出現 pharyngotonsillitis
-受影響的 mucosa 上會有很多大頭針頭樣的水跑,在破裂後會,中央會有 ulceration 並且會有 yellow fibrin 覆蓋
-無論是 movable 或是 attached oral mucosa 都會被影響
-很少越過lip的wetline而影響唇的朱嘉工區(vermilion)
from Neville
The cytologic alterations are virtually identical to those described for HSV. The virus causes acantholysis, with for- mation of numerous free-floating Tzanck cells, which exhibit nuclear margination of chromatin and occasional multinucleation
D 應該是描述 VZV 的特徵吧
但是他在前面在HSV1,2 後也有提到 但是他沒有特別說HSV1,2 就是以 free floating Tzanck cell.... 而是講了ㄧ個概論
HSV-infected epithelial cells exhibit acantholysis, nuclear clearing, and nuclear enlargement (termed ballooning degeneration) (Fig. 7-12). The acantholytic epithelial cells may be referred to as Tzanck cells. (This term refers to free-floating epithelial cells in any intraepithelial vesicle and is not specific for herpes.)