試題詳解

33. A 10-year-old girl is brought by her parents to the dermatologist. She has many freckles on her face, neck, arms, and hands, and the parents report that she is unusually sensitive to sunlight. Two basal cell carcinomas are identified on her face. Based on the clinical picture, which of the following processes is most likely to be defective in this patient?
(A) Removal of pyrimidine dimers from DNA by nucleotide excision repair
(B) Removal of mismatched bases from the 3'-end of Okazaki fragments by a methyl-directed process
(C) Repair of double-strand breaks by error-prone homologous recombination
(D) Removal of uracil from DNA by base excision repair