34. During RNA synthesis, the DNA template sequence TAGC would be transcribed to produce which of the following sequences?
(A) ATCG
(B) CGTA
(C) AUCG
(D) GCUA

30. Producing 100,000 different proteins from 20,000 genes delineates (A) Alternative splicing (B) DNA repair (C) Post-translation modification (D) Elongation

31. What is the molecular event by which the operator of an operon regulates the expression of its structural gene(s)? (A) The operator codes for the repressor, which binds to the structural genes (B) The operator codcs for the repressor, which binds to the RNA polymerase (C) The operator is bound by the repressor, thereby inhibiting RNA polymerase (D) The operator is bound by the regulator gene, thereby inhibiting RNA polymerase

32. What is the best statement regarding protein folding? (A) Protein folding increases the entropy of the system, thus it follows the 2nd law of thermodynamics (B) Protein folding decreases the entropy of the system, thus it follows the 2'd law of thermodynamics (C) Protein folding increases the entropy of the system, thus it violates the 2nd law of thermodynamics (D) Protein folding decreases the entropy of the system, thus it violates the 2'd law of thermodynamics

33. A 10-year-old girl is brought by her parents to the dermatologist. She has many freckles on her face, neck, arms, and hands, and the parents report that she is unusually sensitive to sunlight. Two basal cell carcinomas are identified on her face. Based on the clinical picture, which of the following processes is most likely to be defective in this patient? (A) Removal of pyrimidine dimers from DNA by nucleotide excision repair (B) Removal of mismatched bases from the 3'-end of Okazaki fragments by a methyl-directed process (C) Repair of double-strand breaks by error-prone homologous recombination (D) Removal of uracil from DNA by base excision repair

35. Methylation and subsequent deamination of cytosine produces what type of mutation after one round of DNA replication? (A) C-to-T transversion (B) C-to-T transition (C) G-to-A transition (D) C-to-A transversion HSING UNI

36. As a measure of quality control in translation, which component of the translation machinery is capable of proofreading and editing amino acids? (A) the ribosome (B) Aminoacyl-tR.NA synthetases (C) tRNAs (D) RNA polymerase

37. The hydrogen bonding interactions in a Watson-Crick AT base-pair involve what units in the adenine base? (A) N-1 and the amino group on C-6 (B) N-1 and N-3 (C) N-7 and the amino group on C-6 (D) N-7 and C-8

38. Splice sites in pre-mRNA are marked by two universally conserved sequences contained (A) in the middle of the intron. (B) at the ends of the exons. (C) at the ends of the introns. (D) None of the above

39. An isolate of a mutant bacterium appears to grow more slowly than the wild-type popuiation from (which it was isolated. Further studies showed that the slower growth was due to a markedly reduced DNA polymerase I activity. From this information, one would expect that this organism would also be deficient in the activity of DNA (A) excision repair. (B) recombination. (C) transcription. (D) translation.

40. Which of the following molecules can be considered a final product in the flow of genetic information within a cell? (A) DNA (B) RNA (C) Protein (D) Protein or RNA can be the final product of a gene.