43. Which of the following statements of transamination are CORRECT?

 I. It is characterized by the transfer of an a-keto acid.

 II. The amino donor becomes an a-keto acid. 

Ⅲ. The coenzyme needed is thiamin pyrophosphate (TPP). 

IV. Humans are capable of synthesizing the a-keto acid analog of nonessential amino acids and using transamination to form the amino acids, but are not able to construct carbon skeletons of the essential amino acids. 

V. The a-keto acid acceptor becomes an a-amino acid.
(A)I, II, III
(B)I,II, IV
(C)I, II, III, IV
(D)II, III, IV, V
(E)I, II, IV, V