70. The effect of 5-Azacytosine on gene expression is to
(A) prevent chromatin remodeling.
(B) prevent RNA editing.
(C) remove DNA methylation.
(D) enhance DNA recombination.
(E) remove histone acetylation.

66. Which of the following statements is true? (A) miRNAs are made from long dsRNAs, whereas siRNAs are made from large hairpin precursors. (B) miRNAs are made from large hairpin precursors, whereas siRNAs are made from long dsRNAs. (C) Both miRNAs and siRNAs are made from long dsRNAs. (D) Both miRNAs and siRNAs are made from large hairpin precursors. (E) none of the above

67. Attaching the activation domain of Gal4 to the Tet (tetracycline) repressor creates a hybrid protein that will (A) bind to the Gal4 binding site in response to galactose. (B) bind to the Gal4 binding site in response to tetracycline. (C) bind to the tet operator in response to tetracycline. (D) bind to the tet operator in response to galactose. (E) all of the above

68. In a neuron at rest, which of the following is true? (A) Leakage of sodium ions into the neuron is greater than leakage of potassium ions out of the neuron. (B) Leakage of sodium ions out of the neuron is greater than leakage of potassium ions into the neuron. (C) Leakage of potassium ions into the neuron is greater than leakage of sodium ions out of the neuron. (D) Leakage of potassium ions out of the neuron is greater than leakage of sodium ions into the neuron. (E) Leakage of potassium ions out of the neuron is equivalent to leakage of sodium ions into the neuron.

69. Which is NOT involved in RNA editing? (A) site-specific deamination of adenines (B) site-specific deamination of cytosines (C) guide RNA-directed uridine insertion (D) guide RNA-directed uridine deletion (E) snoRNA-directed 2’-OH methylation

71. Influenza virus has pH-sensitive, acidic fusogenic proteins. Based on this, influenza virus would be expected to fuse with (A) plasma membrane. (B) membrane of trans-Golgi network. (C) membrane of late endosomes. (D) membrane of mitochondria. (E) membrane of peroxisomes.

72. Which of the following statements best compares a pseudocoelom and a coelom? (A) A pseudocoelom is completely enclosed by mesoderm whereas a coelom has an outer covering of mesoderm and an inner one of endoderm. (B) A coelom is completely enclosed by mesoderm whereas a pseudocoelom has an outer covering of mesoderm and an inner one of endoderm. (C) The coelom is enclosed by ectoderm and the pseudocoelom is enclosed by endoderm. (D) The pseudocoelom is enclosed by ectoderm and the coelom is enclosed by endoderm. (E) The coelom is enclosed by ectoderm and the pseudocoelom is enclosed by mesoderm.

73. A partial diploid E. coli with which of the following genotypes would turn blue on the plate containing X-Gal in the presence or absence of the inducer IPTG?(A) I+O+lacZ+ / I+O+lacZ- (B) I-O+lacZ+ / I+O+lacZ- (C) I+OclacZ- / I+O+lacZ+ (D) I+OclacZ+ / I+O+lacZ+ (E) I+OclacZ- / I-O+lacZ+

74. A mutant cell does not have mannose 6-phosphate receptor. Lysosomal enzymes in this cell will (A) not be synthesized. (B) be in the cytosol. (C) be in the ER. (D) be secreted. (E) be in the lysosome.

75. Place the following events of mitosis in the correct order. I. Sister chromatids align on the metaphase plate. II. The cleavage furrow forms. III. The nuclear membrane breaks up. IV. Sister chromatids condense. V. Sister chromatids separate. (A) I, II, III, IV, V (B) III, IV, I, V, II (C) IV, III, I, V, II (D) III, II, I, IV, V (E) IV, I, III, V, II

1相手チームと我がチームの戦力差は五分五分というところだ。 (A)ごふんごふん　　(B)ごぶごぶ　　(C)はんぶんはんぶん　　　(D)ごふごふ