80.下列有關caspofungin的敘述,何者錯誤?
(A)半合成的echinocandin
(B)抑制β-1,3-glucan synthase
(C)可治療新生囊球菌(Cryptococcus neoformans)感染
(D)靜脈注射給藥
統計: A(487), B(738), C(3328), D(1776), E(0) #1632286
詳解 (共 10 筆)
Caspofungin對Aspergillus和Candida有效
Amphotericin B對新生囊球菌(Cryptococcus neoformans)感染引起之腦膜炎有效
8 下列何者可治療 Cryptococcus neoformans 感染?
(A) Fluorouracil
(B) Amphotericin B
(C) Primaquine
(D) Niclosamide
61 下列有關抗黴菌藥物 Caspofungin 之敘述,何者錯誤?
(A)屬於 echinocandin
(B)為環狀 peptide,具有長的脂溶性側鏈
(C)抑制 β-1,3-glucan synthase
(D)用於治療 Cryptococcus neoformans,但對於 aspergillosis 及 candida 感染無效
Caspofungin is a lipopeptide antifungal drug.
It is a member of a new class of antifungals termed the echinocandins.
It works by inhibiting the enzyme (1→3)-β-D-glucan synthase and thereby disturbing the integrity of the fungal cell wall.
Caspofungin was the first inhibitor of fungal (1→3)-β-D-glucan synthesis to be approved by the United States Food and Drug Administration.
Caspofungin is administered intravenously.
Caspofungin對Aspergillus和Candida有效
Amphotericin B對新生囊球菌(Cryptococcus neoformans)感染引起之腦膜炎有效