15. Which of the following descriptions about COVID-19 virus is NOT correct?
(A) The RNA-dependent RNA polymerase is a primary target for anti-COVID-
19 virus drug remdesivir.
(B) Antigenic drit is a kind of genetic variation that can result in a new strain of
COVID-19 virus particles.
(C) Coronaviruses are prone to undergo antigenic shift by combining two
different viruses to make a novel strain.
(D) COVID-19mRNA vaccines contain the instructions for making the SARS-
CoV-2 spike protein
(E) COVID-19 mRNA vaccines require to be stored at an ultra-cold freezer at
temperatures between -80*C and -60*C for up to 6 months.
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統計: A(6), B(4), C(13), D(4), E(2) #3086638
統計: A(6), B(4), C(13), D(4), E(2) #3086638
詳解 (共 2 筆)
#6371962
抗原漂變 (antigenic drift)病毒在「點突變」下,表面抗原(如棘蛋白或血球凝集素)慢慢改變
抗原轉變 (antigenic shift) 整段基因重組(基因重配),產生一整組新抗原,易大流行
ㅤㅤ
COVID-19 的變種(如 Omicron)都是靠棘蛋白(Spike)基因的點突變,不是基因重組
因為Covid為不分段單股RNA,很難像流感(8段RNA)那樣發生antigenic shift~
可以解釋為何我們每年都要重新施打流感疫苗,而不用每年施打covid疫苗
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