35. Protein acetylation is an important mode of regulation. Which of the following statements about reversible protein acetylation is incorrect?
(A) Protein acetylation usually uses acetyl-CoA as the acetyI group donor.
(B) The deacetylation reaction often involves the participation of NAD+ as a cofactor.
(C) The reaction typically occurs at the a-amino group of a lysine in the target
(D) Almost all enzymes in the TCA cycle can be regulated by protein acetylation
(E) Sirtuin-3 is a mitochondrial deacetylase that activates a TCA cycle enzyme - isocitrate dehydrogenase. protein.