試題詳解

46. Many enzyme-catalyzed reactions involved the formation of low-barrier hydrogen bonds (LBHB). Which of the following statements about LBHB is incorrect?
(A) The hydrogen atom is equally distributed between the two heteroatoms (oxygens).
(B) The bond order approaches 0.5 for both O-H interactions.
(C) As the distance between the heteroatoms gets smaller, the H bonds become weaker.
(D) The barriers that must be overcome to exchange hydrogen atoms for oxygen become lower.
(E) The pKa values of the two heteroatoms should be similar.