試題詳解

49. Comparing the ubiquitination and sumoylation pathways, which of the following statements are TRUE?
(1) Both types of protein modification can target proteins for proteasome- mediated degradation
(2) Both types of protein modification can be used to regulate DNA repair.
(3) Before modification, SUMOs need to be proteolytically processed.
 (4) Both types of modification can provide a new binding site for an interacting partner.
 (5) For both types of modification, ligation occurs between a Gly residue on substrate proteins and a Lys residue on the modifiers.
(A) 234
(B) 135
(C) 245
(D) 123
(E) 345