試題詳解

50. Hypoxia condition is a common microenvironment within tumor. Hypoxia might attenuate mitochondrial activity resulting to increased production of lactate. Based on your knowledge , which of the following statements can explain the mechanism correlated hypoxia condition and the production of lactate?
(A) Low ATP production might increase phosphofructokinase activity leading to increase lactate production.
(B) Low ATP production promotes glycogen synthesis leading to inactivation of glycolysis.
(C) High ATP production promotes the carboxylation of Pyruvate leading to gluconeogenesis.
(D) High ATP production inactivates hexokinase leading to decreased of glycolysis.
(E) None of the above.