試題詳解

51. Pyruvate kinase is one of the regulatory enzymes within glycolytic pathway. However, the genetic deficient of this enzyme might affect the normal function of red blood cells. Which of the following scenarios is likely to be observed for pyruvate kinase deficient
(A) The red blood cells contain high level of NADH.
(B) The red blood cells contain low level of 2,3-biphosphoglycerate.
(C) High lactate concentration in blood.
(D) The hemoglobin significantly loss its affinity to bind oxygen.
(E) The TCA cycle in blood cells will be significantly activated.