試題詳解

57. Lesch-Nyhan syndrome is a rare inherited disorder. This disease leads to increased uric acid in all body fluids. In the view of metabolism, the disease is caused by the deficient of
(A) xanthine oxidase
(B) uricase
(C) xanthine oxidoreductase
(D) hypoxanthine-guanine phosphoribosyl transferase
(E) guanine deaminase