74. Which of the following Diels-Alder reactions has the largest reaction rate constant?
(A)
(B)
(C)
(D)
(E)

70. Predict the outcome of the following sequence of reactions. (A) (B) (C) (D) (E)

71. The following substrate is a starting material in the synthesis of compounds having opioid activity. Show all products that would result from the reaction below. (A) I, II, III (B) I, III, IV (C) I, III, V (D) II, III, IV (E) II, IV, V

72. Predict the structure of the hydrolysis product. (A) (B) (C) (D) (E)

73. In order to synthesize the final product shown below, predict when should a protecting group be added and when should it be removed? (A) The hydroxyl group should be protected before step I and removed after step I (B) The hydroxyl group should be protected before step I and removed after step II (C) The hydroxyl group should be protected before step I and removed after step III (D) The hydroxyl group should be protected before step II and removed after step III (E) There is no need for a protecting group in this synthesis.

75. What is the product of this reaction? ?(A) (B) (C) (D) (E)

76. What is the major product obtained from the following reaction sequence? (A) (B) (C) (D) (E)

77. What is the major product of the following reaction? (A) (B) (C) (D) (E)

78. Which of the following reactions is called Gabriel synthesis? (A) (B) (C) (D) (E) None of the above.

79. What is the major product of the following triene to undergo the intramolecular Diels-Alder reaction? (A) (B) (C)  (D) (E)

80. The following reaction involves an intramolecular Michael reaction followed by an intramolecular aldol reaction. What is the major product of this reaction? (A) (B) (C) (D) (E)