阿摩線上測驗
78.下列敘述何者錯誤？[註：myeloablative conditioning（MAC）]
(A)移植前conditioning regimen根據藥品組成及劑量不同，可分為 MAC及RIC
(B)RIC的治療相關毒性較MAC低，但缺點為治療強度較弱，無法完全清除受贈者體內的造血細胞
(C)RIC對於受贈者體內的造血細胞清除能力較低，故應使用骨髓幹細胞作為捐贈來源，較不易有排斥反應
(D)部分接受異體幹細胞移植病人，可在移植後適當時機輸注捐贈者淋巴球，以誘發植體抗血癌反應
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統計： A(93), B(229), C(1438), D(578), E(0) #3197696
統計： A(93), B(229), C(1438), D(578), E(0) #3197696
詳解 (共 5 筆)
邱子 安
#6165032
C選項
Allogeneic HCT for malignancies — For allogeneic HCT to treat a cancer, the preferred graft source is guided by the transplant recipient's age.
For adults undergoing allogeneic HCT for a malignancy, we suggest peripheral blood grafts rather than bone marrow grafts.
For children undergoing HCT for a malignancy, we suggest bone marrow grafts rather than peripheral blood grafts, based on similar or better survival outcomes and less GVHD.
ref: UpToDate Hematopoietic cell transplantation (HCT): Sources of hematopoietic stem/progenitor cells
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